Caution should be exercised when administering promethazine hcl to pediatric patients 2 years of age and older.
Information about Promethazine.
Parenteral25 mg IV or IMfollowed by close observation for responseThis dose may be repeated within 2 hours if neededOral therapy should be started as soon as feasible if continued medication is required.
Although primarily used to treat allergiesPromethazine is indicated to treat a variety of other conditions as well.
Since promethazine HCI administered intravenouslyby injectioncan cause severe chemical irritation and damage to tissuesdeep intramuscular injectiona technique administering medication deep into the musclesis the preferred method of injectionPromethazine hydrochloride injections should not be given by intra-arterialwithin an arteryinjectionunder any circumstancesdue to the risk of severe arteriospasmspasm in an arteryand resulting gangrene.
The safety of promethazine for long-term treatment of allergic rhinitis has not been established.
Promethazine hydrochloride tablets may lower seizure thresholdThey should be used with caution in persons with seizure disorders or in persons who are using concomitant medicationssuch as narcotics or local anestheticswhich may also affect seizure threshold.
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cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can interact with promethazine and cause medical problems or increase side effects.