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The change in visual acuity may be unilateral or bilateral and hence each eye must be tested separately and both eyes tested togetherTesting of visual acuity should be performed before beginning Myambutol therapy and periodically during drug administrationexcept that it should be done monthly when a patient is on a dosage of more than 15 mg per kilogram per daySnellen eye charts are recommended for testing of visual acuityStudies have shown that there are definite fluctuations of one or two lines of the Snellen chart in the visual acuity of many tuberculous patients not receiving Myambutol.
Myambutolfollowing a single oral dose of 25 mg/kg of body weightattains a peak of 2 to 5 mg/mL in serum 2 to 4 hours after administrationWhen the drug is administered daily for longer periods of time at this doseserum levels are similarThe serum level of Myambutol falls to undetectable levels by 24 hours after the last dose except in some patients with abnormal renal functionThe intracellular concentrations of erythrocytes reach peak values approximately twice those of plasma and maintain this ratio throughout the 24 hours.
You should seek medical advice in relation to medicines and use only as directed by a healthcare professional.
Tell your doctor and pharmacist about all of your drugsprescription or OTCnatural productsvitaminsand health problemsYou must check to make sure that it is safe for you to take Myambutolethambutolwith all of your drugs and health problemsDo not startstopor change the dose of any drug without checking with your doctor.
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