No dose adjustment of femara is required for patients with mild to moderate hepatic insufficiency child-pugh a or b .
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Clomidclomipheneis an oral medication used for stimulating ovulationClomid is prescribed to stimulate ovulation in women with ovulatory dysfunction who are not pregnantdo not have abnormal bleeding or ovarian cystsand have normal liver functionIt binds to estrogen receptors in the hypothalamuspituitary glandovaryendometriumvaginaand cervixIt causes production of hormonesgonadotropinsby the pituitarywhich stimulates ovulation.
Adjuvantpost-surgerytreatment of hormone receptor positive invasive early breast cancerExtended adjuvant treatment of hormone-dependent invasive breast cancer in women who have received prior standard adjuvant tamoxifen therapy for five yearsFirst-line treatment for hormone-dependent advanced breast cancerAdvanced breast cancer after relapse or disease progressionin women with natural or artificially induced postmenopausal endocrine statuswho have previously been treated with anti-oestrogensNeo-adjuvantpre-surgerytreatment of hormone receptor positiveHER-2 negative breast cancer where chemotherapy is not suitable and immediate surgery not indicated.
Aromatase inhibitor medications can cause joint or muscle aches and painswhich can interfere with quality of lifeBe sure to talk to your oncology care team if you develop this side effectThis pain is caused mainly by swelling in the jointswhich is best treated by a non-steroidal anti-inflammatoryNSAIDsuch as ibuprofenAdvil/MotrinnaproxenAleveand celecoxibCelebrexBe sure to discuss which pain relievers you can safely take with your oncology teamas these are not without their own side effectsStudies have shown that acupuncture and gentle stretching and exercise may also help reduce this pain.
Femara is a medicine that contains the active substance letrozoleIt is used as hormonal treatment in postmenopausal women with breast cancer.
2.5mg once dailyAdjuvant or extended adjuvant therapydiscontinue at tumor relapsesee full labelingAdvanced breast cancercontinue until tumor progression is evidentSevere hepatic impairment or cirrhosis2.5mg every other day.
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