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In female hypertensive patients the plasma levels of losartan were up to twice as high as in male hypertensive patientswhile the plasma levels of the active metabolite did not differ between men and women.
If you are using the liquid form of this medicationshake the bottle well before each doseCarefully measure the dose using a special measuring device/spoonDo not use a household spoon because you may not get the correct dose.
If symptomatic hypotension should occursupportive treatment should be instituted.
Kidney problemslittle or no urinationpainful or difficult urinationswelling in your feet or anklesfeeling tired or short of breath.
A lower dose should be considered for patients with a history of hepatic impairmentThere is no therapeutic experience in patients with severe hepatic impairmentThereforelosartan is contraindicated in patients with severe hepatic impairmentsee sections 4.3 and 4.4
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