Clinical studies showed that people who were undetectable on another regimen could safely switch to viramune.
Information about Viramune.
An increase in weight and in levels of blood lipids and glucose may occur during antiretroviral therapySuch changes may in part be linked to disease control and life styleFor lipidsthere is in some cases evidence for a treatment effectwhile for weight gain there is no strong evidence relating this to any particular treatmentFor monitoring of blood lipids and glucose reference is made to established HIV treatment guidelinesLipid disorders should be managed as clinically appropriate.
No clinical data availableDue to the metabolic pathway of raltegravir no interaction is expected.
Patients who interrupt nevirapine dosing for more than 7 days should restart the recommended dosing regimen using the two week lead-in period.
The limited data available with saquinavir soft gel capsule boosted with ritonavir do not suggest any clinically relevant interaction between saquinavir boosted with ritonavir and nevirapine.
Serum levels of nevirapine can be reduced by concomitant use of the herbal preparation StJohn’s WortHypericum perforatumThis is due to induction of medicinal product metabolism enzymes and/or transport proteins by StJohn’s Wort.
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