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Prolonged prothrombin timeincreased blood urea nitrogenBUNincreased creatinineelevated alkaline phosphataseelevated bilirubinelevated lactate dehydrogenaseLDHpancytopenialeukopeniaand agranulocytosis.
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Prolonged use of KEFLEX may result in the overgrowth of nonsusceptible organismsCareful observation of the patient is essentialIf superinfection occurs during therapyappropriate measures should be taken.
For more severe infections larger doses of oral KEFLEX may be neededup to 4 grams daily in two to four equally divided doses.
Because clinical trials are conducted under widely varying conditionsadverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
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