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If corticosteroids are used at excessive doses for prolonged periodssystemic corticosteroid effects such as hypercorticism and adrenal axis suppression may occurFor chronic overdosage in the case of severe disease requiring continuous steroid therapythe dosage may be reduced temporarily.
Hypercorticism and adrenal axis suppressionsee WARNINGS AND PRECAUTIONSSymptoms of steroid withdrawal in those patients transferred from other systemic corticosteroidssee WARNINGS AND PRECAUTIONSIncreased risk of infectionsee WARNINGS AND PRECAUTIONSOther corticosteroid effectssee WARNINGS AND PRECAUTIONS
Hypoadrenalism may occur in infants born of mothers receiving corticosteroids during pregnancyInfants should be carefully observed for signs of hypoadrenalismsuch as poor feedingirritabilityweaknessand vomitingand managed accordinglysee WARNINGS AND PRECAUTIONS
Treatment of active mild-to-moderate Crohn disease involving ileum or ascending colonmaintenance of clinical remission of mild-to-moderate Crohn disease for up to 3 months.
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